لوسمي حاد لنفوبلاستيك ثانويه به دنبال درمان موفقيت آميز تومورويلمز:معرفي 1مورد

Secondary Acute Lymphoblastic Leukemia Following a successful Treatment of Wilmʹs Tumor: A Case deport

Secondary Malignant Neoplasm(SMN) is one of the late effects of childhood cancer. Among secondary malignancies, acute myeloid leukemia(AML) is the most common and life-threatening neoplasm. Secondary acute lymphoblastic leukemia(ALL) is rare and only 10% of SMN is ALL. Patients with Wilmʹs tumor are not protected from the secondary cancers after the primary diagnosis. Among patients with this tumor the most common SMN is AML and ALL is very rare. In this paper, we report a case of ALL, four years after diagnosis of Wilmʹs tumor. The patient died nineteen months after the beginning of leukemia treatment due to multiple relapse and resistance to treatment. With advances in the treatment of childhood cancer, more children are surviving long periods of time; therefore, careful follow-up and other examination sequels are necessary for early diagnosis of SMN.