مقايسه ارزش تشخيصي سيتولوژي حين عمل جراحي و برش انجمادي در بدخيم هاي پستان

INTRAOPERATIVE CYTOLOGY AND FROZEN SECTION IN THE DIAGNOSIS OF BREAST MALIGNANCY: A COMPARATIVE STUDY

We prospectively studied the usefulness of intraoperative cytology (directed scrape preparation) and frozen section in the diagnosis of 100 breast lesions (53 benign and 47 malignant). This study used sensetivity, specifity and accuracy as statistical tools based on binary principles. The intraoperative results have been compared with the final histological diagnosis, Intraoperative cytology as compared to histopathology had 90% accuracy, with 85% sensetivity and 94.3% specifity. Frozen section was more accurate than intraoperative cytology as compared to histopathology(accuracy 98%, sensetivity 95.7% and specifity 100%). However the differences were not statistically significant (P>0.05). These data confirm the value of intraoperative cytology in the diagnosis of breast malignancy and suggest that it could be used as an alternative to frozen section, if technical condition required for frozen section are not available or suitable.