سنجش مقاومت آنتي بيوتيكي ويبريوكلراهاي جداشده از نمونه هاي مدفوع در تابستان 1377 در تهران

ANTIBIOTIC RESISTANCE OF THE VIBRIO CHOLORAE STRAINS ISOLATED FROM CLINICAL SAMPLES

Three hundred and fifty samples from the patients suspected of having Chalerae were examined at the department of Bacteriology, Pasteur Institute of Iran. Using standard biochemical tests and agrouping, 140 samples were identified as the Vibrio choleiae; positive specimen. One hundred and six samples had a biochemical pattern compatible with the biotype Etta vibrio. Group specific sera identified 139 and 1 strains as ogawa and non- agglutinable (NAG), respectively. Antibiotic susceptibility test indicated that all strains were sensitive to ciprofloxacin and gentamycin. The resistance to doxycycline, chloramphenicol and erythromycin were found to be 2.9%, 2.2% and 8.6%, respectively. Furthermore, a significant resistance was found with cotrimoxazole, oxytetracycline and tetracycline with 98.6%, 87.6% and 61.9%, respectively. The betahemolysis reaction revealed that V. cholerae biotype Eltor may not always show a positive hemolysis. Overall, the data indicated that constant monitoring of the antibiotic susceptibility pattern of V. cholerae in Iran is essential.