بررسي مقايسه اي اثر سيتانست و مپي واكايين بر روي فشارخون بيماران مبتلا به فشارخون بالا

A comparative study between citanest and mepivacaine on high blood pressure in hypertensive patients

Background and aim: Selection the proper local anesthesia drug in dental procedures especially for patients with cardiovascular problems is very important. Recently, a lot of studies have been conducted on local anesthetic drugs such as mepivacaine, prilocain cane particularly lidocaine but much attention has not been paid to homodynamic effects of prilocain associated with citanest as a vasoconstrictor tletl are recommended for cardiovascular patients. The aim of the present study was to compare the effects of citanest and mepivacaine on blood pressure of hypertensive patients. Materials and Methods: In this clinical study, 18 hypertensive patients (15 females, 3 males), referred to Isfahan dental faculty, with the mean age of 49.7, who needed extraction or mandibular surgery, were selected. Mepivacaine was injected in one session and citanest in later session. The injection was interior alveolar nerve block for all patients, Each patient,s blood pressure and pulse rate were measured during, after 5 and 10 minutes of injection. Data were collected and analyzed by SPSS - 4 software and repeated measure analysis test. Results: Average pulse rate and blood pressure (systolic and diastolic) after 5 minutes for citanest were 0.77±2.81, 0.36±1.34 and 3.3±{).77, respectively and after 10 minutes were 0.55±3.11, 0.24±1.39 and 0.23±1.55, respectively. For mepivacaine after 5 minutes these figures were in order 0.77--±-5.2, 0.5±0.9 and 0.12±0.48 and after ten minutes were in order 0/88±5.29. 0.3±1.03 and 0.17±0.54. No statistically significant diffrernee was found between two drugsin all cases. Conclusion: The findings of this study show that two local anesthetic drugs: citanest with vast) constriction and mepivacaine without vasoconstriction in cardiovascular patients affected wish hypertension have equal effects in dentistry procedures.