گواتر هيپراندميك در راويز رفسنجان ، احتمال وجود گواتروژن هاي ناشناخته

Hyperendemic Goiter in Raviz of Rafsanjan: Are there Other Unknown Goiterogens?

Introduction: Endemic goiter due to Iodine deficiency is one of the health problems in devloping (loping countries including Iran. So, national committee for control of Iodine dificiency disorders has planned Iodine salt from 1368. The purpose of this study was to evaluate goiter and its relation with urinary Iodine excretion in schoolchildren in vill of Raviz (Raviz Includes 6 small-villages) of Rafsanjan. Material and Methods: All of the 320 schoolchildren (boys and girls) 6-12 years old, in were examined for goiter and classified according to WHO classification and their urinary Raviz excretion was measured. Drinking water iodine of Raviz was also measured. Results: 87.34% of girls and 81.47% of boys had different grades of goiter. The majority were found grade I and II. 25% of schoolchildren had severe urinary Iodine defeciency (<2 µg/dl), 4.4% moderate (2.1-4.9 µg/dl and 10.3% mild (5-9.9 µg/dl). The concentration of urinary iodine I" t;0.3% of schoolchildren were more than 10ug/dl (normal). From 6 small - villages of vill of Raviz which this study was carried out, only in one village concentration of Iodine in the ʹ1i inking water was 15.2µg/dl, but in others were less than 2 µg/dl. Conclusion: Although the concentration of Iodine in drinking water in 5 small-villages of Raviz was less than 2µg/dl, but in 60.3% of schoolchildren urinary Iodine were found to be normal So Iodized salt consumption has had considerable effects on control of Iodine deficiency. Another possibility is present of unknown goitrogenes in this area that should be discovered by rim her investigations.