كنترل ميكربي تعدادي از داروهاي گياهي ساخت داخل كشور

Quality control of some Iranian herbal drugs

Herbal drugs such as those in other pharmaceutical articles may be contaminated by microorganisms during process and production. Ever-increasing attention for the use of herbal drugs which are offered in dosage form necessitate their quality control. So the quality assurance of herbal drugs in dosage form must be considered by the physician and patients interested in using them. In this study the estimation of number of viable aerobic microorganism numbers present and pharmaceutical freedom from designated microbial species according to USP method were taken in some products, i. e. tablets, powders and drops. In tablets and powders the most probable number was more than 1,100 per gram. But there were no microorganisms in the drop specimens. The powder specimens were contaminated with Salmonella and Escherichia colt, but not Condida alhicans. Other microbial contamination were evaluated, and tablet specimen contamination with Bacillus circulans was established.