NCEP- ATPIII بررسي ميزان تظابق درمان هيپرليپيدمي با درمان پيشنهادي برنامه ملي آموزش كلسترول

A Comparison of Hyperlipidemia Management by Physicians of Yazd and the National Cholesterol Education Program (NCEP) guidelines

Introduction: We sought to compare methods currently used by physicians of the city of Yazd to treat hyperlipidemia and the standard recommended treatment of the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATPIII). Methods and Materials: An observational, cross-sectional study was conducted on 146 adult patients, selected by random stratified sampling, from among patients admitted to medical diagnostic laboratories of Yazd. Inclusion criteria were: concentration of TG and Cholesterol ? 200mgIdL (or more) observed, following first visit to a physician. Serum of patients was collected for measuring HDL (and LDL) and a questionnaire was completed before and after treatment. The method used by these physicians was then compared to the NCEP-ATPIII recommended standard treatment. Results: From 146 patients that participated in our study, 85 patients (58.2%) were female, 49 patients (33.6%) had DM, 11 female patients (12.9%) had had premature menopause, 9(6.2%) had a family history of early coronary disease, 8(5.5%) were smokers and 43(29.5%) had hypertension. Mean number of ischemic heart disease (I.H.D) risk factors in females were significantly less than in males (p=0.000). Mean H.D.L and cholesterol in females were significantly higher than in males (p=0.038 and p=0.031 respectively). Only 86 patients (58.9%) were treated according to recommended NCEP guidlines. Undertreatment was most common (31.5%). Patients with D.M., positive history of I.H.D, and LDL concentration over 160 mg1dL were more mismanaged. Conclusion: Physicians of Yazd poorly comply with NCEP-ATPIII, a problem is more noticeable in-patients at high risk for I.H.D.