اثر ويتامين ها و مينرال ها بر ميزان چربي خون افراد ديابتي نوع 2

Impact of vitamin and/or mineral supplementation on lipid profiles in type 2 diabetes

Introduction: The purpose of the present study was to assess the impact of Mg+Zn, vitamin C+E, and combination of these micronutrients on serum lipid and lipoprotein profiles in type 2 diabetic patients. Material and Methods: In a randomized, double blind, placebo controlled clinical trial, 69 type 2 diabetic patients under diet and hypoglycemic drugs were randomly divided Into four groups. Each group received one of the following daily supplement for 3 months; group M: 200 mg Mg and 30 mg Zn (n=16), group V: 200 mg vitamin C and 150 mg vitamin E (n=18), group MV: minerals plus vitamins (n=17), group P: placebo (n=18). Results: Results indicate that after 3 months of supplementation mean serum levels of HDL-c and apolipoprotein Al increased significantly In the MV group by 24% (50.4±19.3 vs. 40.6110.8 mg/dL) and 9% (170134 vs. 156±24 mg/dL), respectively (p<0.01). There were no significant changes in the levels of these parameters in the other 3 groups. Serum levels of total cholesterol, LDL-c, triglyceride, and apolipoprotein El were not altered after supplementation in all 4 groups. Conclusion: It is concluded that since co-supplementation of Mg, Zn, vitamin C and E significantly increases HDL-c and apolipoprotein Al, supplementation of these micronutrients should be recommended for type 2 diabetic patients based on their daily requirements.