بررسي تيتر HBSAB در كودكان 8 ساله واكسينه شده در مدارس شهرستان يزد در سال 1380

Viral Hepatitis is still a major hygienic problem in both developing and developed countries . The Hepatitis B vaccine is important for fighting against the hepatitis B virus and preventing its chronicity.The purpose of this study was to inspect the effectivity of immunity of hepatitis B vaccine seven years after the Iranian Public Vaccination Program. The search was a descriptional and a cross sectional one . The surveyed society included Yazd primary school 8 year old students who had been vaccinated 2 or 3 times according to the public vaccination program. 200 samples with an equal number of boys & girls were included in the study. 69% of the society was positive 7 years after injection ( HbsAb>10mlu/ml). Seventy one percent boys and 67% girls were positive HbsAb . The children with high BMI had low positive HbsAb. The was no clear difference between the group with birth weight<2500 gr and the group with birth weight > 2500 gr regarding positive HbsAb. Considering the results of the above study, with reference to the immunity permanence 7 years after vaccination (69%), which confirms with similar researches of other countries- a booster dose is not recommended.