تعيين ميزان شيوع ويروس هاي پاراآنفلوآنزا و آدنوويروس در عفونت هاي مجاري تنفسي تحتاني بيماران بستري شده مازندران طي سال هاي 80-1381

Study on the prevalence of parainfluenza and adenovirus lower Study on the prevalence of parainfluenza and adenovirus lower

Background and purpose: There are different etiological agents of lower respiratory tract infections in children. Rate of their role is based on the age of patients, season, geographical areas and the used diagnostic methods. Aim of this study is to determine rate of infections caused by these viruses in the patients admitted for lower respiratory tract infection Materials and methods: Children of 1 month to 10 years of age, infected with lower respiratory tract infection, admitted in Boali sina and Amir kola hospitals were studied for the presence of adenovirus and parainfluenza viruses. Indirect Immunofluorescent method was used to study the pharyngeal and nasopharyngeal discharges. Then their relationship with clinical, laboratory and radiological findings were analyzed. Results: Duping 7 months period of this study (march to september), 150 children with age ranges of 1 month to 8 years were admitted. 60 viruses were isolated from 56 patients (in 4 cases, two viruses together). The rates of isolated viruses were as follow: parainfluenza virus type 3 18% , type 1 and 2 8% and 7.3% respectively, and adenovirus 6.7%. Children under 2 years had the highest rate of infection and consisted 70% of all patients. Conclusion: The above mentioned viruses, play very important role in respiratory tract infection in children. The role of viruses, bacterial agents and their relation with different clinical, laboratory and radioloagical findings be studied for years to come is recommended, in order to clear the relation between various agents and clinical syndromes, so, to be able to have proper treatment program for the area.