بررسي اثرپيشگيرانه كلونيدين بر روي لرز بعد از عمل

Prophylactic Effect of the Clonidine on the Post-operative Shivering

Background and Objectives: Recovery from anesthesia may he associated with numerous complications. Postoperative shivering is one of these complications that strongly increases body oxygn consumption, and may be dangerous in patients with coronary artery disease and heart failure. The purpose of this study, was to investigate the effects of clonidine on the post-operative shivering. Materials and Methods: In a prospective study, one hundred patients were randomly selected in Shohada, Al Zahra and Nicoukary Hospitals and divided in two groups: Group A (study group, n = 50) and Group B (Control group, n = 50). In group A, 0.2 mg clonidine was given before anesthesia and in group 13, only placebo was provided. In these patients blood pressure and heart rate were measured preoperatively and intraoperatively. Effect of the type of surgery and duration of operation, was also studied upon post-operative shivering. Results: Occurance of shivering was decreased in group A (12%) as compared with group B (32%) (p = 11.03). There were significant differences between types of operation and duraion of operation with shivering incidence. There were also significant differences in intraoperative blood pressure between the two groups. Conclusion: The results of this study suggest that clonidine with its centeral effects is associated with decreased (approximately 20%) prevalence of shivering in post-operative patients.