كليدواژه :
پزشكي , Obsessive - compulsive disorder , Treatment outcome , عوامل پيش بيني كننده سير , نتايج درماني , Prognostic factors , اختلال وسواس جبري
چكيده لاتين :
Background and Objectives: Few studies have been carried out about treatment outcome of obsessive compulsive disorder (OCD). In this study the role of age, sex, duration of disorder, family history and co morbidity in treatment outcome of obsessive-compulsive disorder were investigated.
Materials and Methods: One hundred patients (47 males, 53 females) were treated with anti- obsessive compulsive drugs (Clomipramine-fluoxetine) for one year. The age of patients ranged between 12 and 69 years. The severity of the disease and the course of improvement in the begining and end of the study were evaluated with psychiatric clinical examinations. Fourteen patients were dropped out. Forty nine females and 37 males completed the study.
Results: Significant improvement was related with the age of patient (significant improvement was noted in 62% of patients under 21 years old, 41%of patients 22-31 years old, and 25% of 32-41 years old patients). Sex had significant importance in the course of improvement (51% males improved better as compared to 49% females) (p<0.05). Duration of the disease was reversely related to significant improvement. Significant improvement was noticed in 60% of cases with duration less than one year, 55% of cases between I and 5 years, and 41.5% of cases between 6-10 years. Family history of the presence or absence of disorder was not significant in treatment outcome. Patients with compulsion (only) had the best outcome. Co morbidity had no significant effect on the course of the disorder.
Conclusion: Finally, it can be assumed that early treatment of the disorder has significant importance in the prognosis of obsessive - compulsive disorder.
