مقايسه اثرات درماني امپرازول و راينيتيدين در يكصد بيمار مبتلا به زخم پپتيك اثني عشر

A Comparison of the Therapeutic Effects of Omeperazol and Ranitidine in 100 Patients with PUD

This study was conducted since no such study had been carried out so far. Refferal patients with symptoms of dyspepsia were confirmed to have PUD after endoscopy and divided into two groups of 50 . Group A recived 20 mg omeperazol orally before breakfast ; group B received 150 mg Ranitidine orally twice a day , after breakfast and dinner . After two weeks, the clinical symptoms and rates of ulcer healing were confirmed by endoscopy . In group A, epigastric tenderness decreased from 32% to 4%, PV prevalence decreased from 30% to 14 % and PU prevalence decreased up to 60%. The results indicated that the efficacy of Omeperazol was significantly higher than that of ranitidine in the treatment of PU (P