بررسي سابقه مصرف مواد مخدر و ساير عوامل خطر زا در بيماران مبتلا به كله سيستيت حاد عمل شده

Evaluation of Risk Factors and Addiction to Opiates in 100 Consecutive Operated Patients with Acute Cholecystitis

Background and Objectives:The roles of contractility disorders of gallbladder and bile stasis have well been defined in the development of gallbladder diseases. Opium addiction may be causative in this view. Materials and Methods: We prospectively studied 100 consecutive patients with acute cholecystitis underwent early open cholecystectomy regarding variables like age, gender, parity, obesity, oral contraceptive, addiction to opiate, socioeconomic problems and other systemic diseases. Results: In this study there was a higher prevalence of biliary tract disease in the patients with positive history of addiction to opiates. Conclusion: It is clear from this study that older females, multipar patients with the history of opium usage have increased risk of biliary tract disease and gallstone formation, and stasis, which includes temporary cessation of bile-flow into the intestine and stagnation in the gallbladder. This has also been assigned as a major role in functional disorder and stone formation and diseases.