بررسي مقايسه اي اثرليدوكايين ، فنتانيل و پلاسبو بر تغييرات هموديناميك به دنبال ساكشن لوله داخل تراشه در بيماران بستري در ICU

Comparison Between Lidocaine , Fentanyl and Placebo on Hemodynamic Changes after intratracheal Suction in iCU Patients

Suction of endotracheal tube in ICU can cause hemodynamic changes. We compare the effect of Iidocaine , fentanyl and placebo on reducing hemodynamic changes following suction in ICU patient. Patients were divided into three groups , each containing twenty two patients: A- Lidocaine group receiving 1.5 mg/kg Iidocaine intravenously two minutes before suction , B- Fentanyl group receiving 3 µg/kg fentanyl two minutes before suction , C- Placebo receiving distilled water . The total volume of the three substances was raised to 5 cc. Injecting the drugs and suctioning in a standard technique , we recorded mean arterial pressure , pulse rate , arterial oxygen saturation three times : immediately , after three and six minuteʹs . The recorded information was analyzed. Based on the results , the injection of Lidocaine before suctioning prevented the hemodynamic changes and hypoxemia , which happened after endotracheal suction. Fentanyl caused hypotension and bradycardia , rejecting the previous reported research. Suctioning in the placebos resulted in hypotension , bradycardia and hypoxemia. We can use intravenous Iidocaine before endotracheal suction to prevent hemodynamic changes in ICU patients.