مطالعه همبستگي تشخيص هاي سيتولوژي و بيوپسي دهانه رحم

A STUDY TO DETERMINE THE CORRELATION BETWEEN CYTOLOGICAL DIAGNOSIS AND BIOPSY OF THE UTERINE CERVIX

The cytological smear and biopsy of cervix are screening and diagnostic tools detection of cervical intraepithelial neoplasia (CIN) and invasive carcinoma. Any discrepancy between cervical cytological and histological diagnosis may cause under or over treatment or even a missed diagnosis. To investigate the causes of discrepancies between cervical cytological and histological diagnosis in our center. Slides of 54 cervical punch biopsies and related cervical smears were collected and reviewed during two years. From a total of 54 cases, 44(81.5%) showed correlation between histologic and cytologic diagnosis before review. Ten cases which had discrepancy between those diagnoses decreased to five after review. The leading cause of discrepancy was interpretative error which were six in histology and four in cytological interpretation. 17 cases which were diagnosed as CIN and invasive carcinoma decreased to 12 cases after review. The second cause of discrepancy was inadequacy of specimens 13 biopsy specimens and 6 pap smear specimens were considered in adequate for proper diagnosis. Careful screening of the papsmears and biopsies, especially those suspected to be CIN and consultation of difficult cases with other pathologists can decrease interpretation errors & improve diagnostic accuracy.