بررسي ارتباط بين نوتروفيلي و نارسايي احتقاني قلب بعد از سكته قلبي

Background and Objectives: Acute myocardial infarction (MI) isʹusually accompanied by leukocytosis and increased neutrophils. However , still it has not been definitely recognized that whether this process is caused by myocardial defects or not. Few studies are availale which have reported about the relationship between neutrophil and short - term risks of myocardial complications such as congestive heart failure(CHF) after MI. In this case neutrophil count can be used as a predictor for CHF in patients with acute myocardial infarction . Materials and Methods: A sectional study was carried out on a population of patients with MI who had been hospitalized in CCU units. Blood samples were withdrawn from all of the patients to count neutrophils and also all interfering agents that could cause an increase in WBC counts were eliminated. Results: Total 50 patients , 84% men and 16% women , were studied. Among these 50 patients , 25 patients were affected by CHF (Ejection Fraction<40%). 32 patients (66%) showed relative neutrophilia (Neutrophil count>66%) while 36% showed no neutrophilia .Two groups were compared by T-test with respect to the average percent of neutrophils and the difference significant statistically ( p=0.001). Totally among 54% of patiants who had been affected by CHF,92% showed relative neutrophilia (N> 65 % ) at the beginning. Conclusion: This study clearly indicates that the presence of relative neutrophilia in patients with acute MI during the early 12-houre period is completely related to the incidence of CHF at first 4 days.