مقايسه يافته‌هاي پرفيوژن مغز به روش SPECT با تصويربرداري‌هاي آناتوميك در بيماران با سابقه تروماي سر خفيف‌

Comparison of brain perfusion S(PECTa6normafities with anatomical imaging in mild traumatic 6rain injury

Background: Trauma is the most common cause of morbidity and mortality in industrialized countries and also in Iran. Anatomical imaging {AI; CT and MR J) is helpful in the diagnosis of acute traumatic complications however it is not efficient in the diagnosis of disabling injury syndrome. In contrast, brain perfusion SPECT (Single Photon Emission Computed Tomography) can be more useful for evaluation of microvascular structure. This study was designed to compare these two diagnostic methods. Methods: A total of 50 patients who had been suffering from traumatic brain injury for more than I year, and were followed as mild traumatic brain injur)ʹ group according to "the Brain Injuryʹ Interdisciplinary Special Interest Group of the American Congress of Rehabilitation Medicine1ʹ criteria, were examined by brain perfusion SPECT and Al. The common anatomical classification of the lobes of brain was used. Results: The male to female ratio was 3:2. The mean age was ^2.32^1 l.X years and mean post-traumatic time was E48±0.65 years. The most common symptoms were headache (60%). agusia (36%) and anosmia i .»). Among 400 examined brain lobes in this study. brain perfusion SPEC! revealed remarkable abnormality in 76 lobes (19%). but AI determined abnormalities m 3N lobes (9.5%): therefore, SPECT was iwicc sensitive than Al in mild traumatic brain injurv (P<().001). The correlation between SPEC! and Al findings was 84%. SPICT was more sensifi\e than AI in demonstrating brain abnormalities jn frontal lobe; it was more obvious in the male group: however, there was no significant difference between more and less than 30 years old groups. Conclusion: According to the findings of this study, we recommend using brain perfusion SPECT for all patients with chronic complications of head trauma, particularly those who have signs and symptoms of hypofrontalism, even though with some abnormalities in Al.