كليدواژه :
پزشكي , پيوند كليه , بيماري قند , diabetes mellitus , Transplantation , ارولوژي , ديابت , اورولوژي , عوامل خطرساز , risk factors , جراحي
چكيده لاتين :
In our study, in addition to determination of frequency of appearance of aggravation of diabetes in our patients, we considered suggesting some risk factors which can predict the appearance of aggravation of diabetes in order to control the diabetes in its early stages. Recorders of 127 patients who had been transplanted in Sina hospital during years 1376-78, were studied. Patients were divided into 2 general groups before transplantation: diabetic and non-diabetic. The frequency of appearance or aggravation of diabetes in each group was determined and in each case, its distribution according to age, sex, blood levels of cyclosporine, Cholesterol, TG, Cr, duration of dialysis, acute rejection and source of transplanted kidney was detetmined. Graft survial after one year was also determined. Before transplatation, 7 patients had diabetes. In non-diabetic group, 14 patinet (11.7%) had got diabetes. By increasing age, duration of dialysis, blood levels of cyclosporine, cholesterol, creatinine and also female sex, the percentage of appearance of diabetes was higher. In diabetic group, all the patients (100%) had aggravation of diabetes. All these diabetic patients and also those who had post transplantation diabetes, had functioning graft after one year and no acute rejection was seen. The source was living doner in former patients. Relative frequency of post transplantation diabetes appearance and aggravation was 11.7% and 100% respectively. It is probable that variables such as blood levels of cyclosporine, cholesterol, creatinine, duration of dialysis, sex and age can be used as predictors of appearance or aggravation of diabetes in transplanted patients. If it becomes true, early diagnosis and treatment of diabetes will be held in order to give and end to the effects of diabetes in transplanted patients.
