گزارش دو مورد پرزانتاسيون نادر آبسه كبد در شيرخواران

PYOGENIC LIVER ABSCESS IN INFANTS ASSOCIATED WITH GENERALIZED EDEMA(REPORT OF TWO CASES FROM AHWAZ)

Pyogenic Liver Abscess (PLA) is a rare disease in normal infants and its presentation is usually nonspecific. PLAs occur in infants and are asseciated with sepsis, umbilical vein infection or vessel cannulation. The major cause of generalized edema occurring before 3 months of age is Congenital Nephrotic Syndrome (CNS). The most common and the best known of all types of CNS is the Finnish type, which is an autosomal recessive disorder (with poor prognosis). In this report two infants with PLA who presented with generalized edema several weeks after birth are presented. They were hospitalized as the Finnish type of CNS. The parents of both cases was first cousins. There was a history of hospitalization due to sepsis and exchange transfusion in the ease 1 and meconium aspiration in the case No 2. Serum albumin in both was less than 2.5g/dl and patients had mild transient proteinuria. After administration of low-salt human albumins and decrease in ascites, hepatoanegaly was diagnosed. Initially, in abdominal ultrasonography & then in abdominal C/T scan, liver tumors were diagnosed. Lapratomy was done and in both cases PLA was established. In the pathology microbiology reports. PLA was confirmed. Both infants were discharged without edema and in good conditions 2-3 weeks after operation and given IV antibiotics and several human albumins. We concluded that in any case with a picture of CNS, other causes of generalized edema including PLA should be initially ruled out.