بررسي فراواني و علل بروز تب در بيماران بستري شده با تب و نوتروپني در طول يك دهه در بيمارستان بقيه الله الاعظم (عج )

A Study on the Prevalence and Etiology of Fever in Hospitalized Patients with Fever and Neutropenia in Baqyiatallah Hospital during 1995-2005

Introduction: Inspite the fact that applying high doses of chemotherapeutic drugs is a successful way to manage patients with cancer, this management reduces the level of immunity. Decrease in neutrophilic cells has caused serious infections and increased mortalities. Thus, This investigation was done to study the prevalence and etiology of fever in hospitalized patients with fever and neutropenia in Baqyiatallah hospital. Materials & Methods: This descriptive cross-sectional study was carried out on 95 hospitalized patients with fever and neutropenia in Baqyiatallah hospital in the decade from 1995 to 2005. Results: 44.2% and 60% of patients were documented microbiologically and clinically for infections. Most common sources of infection in patients were Pulmonary (17.9%) and urinary tract (10.5%) infections. In 29.5% and 7.4% of infectious cases, gram-negative and positive bacteria were isolated respectively. Conclusion: Unlike the most previous reports Mentioning gram-positive bacteria as a main cause of fever in these patients, in current study Escherichia coli proved to be the most common organism isolated.