بررسي بروز بدخيمي هاي جديد پس از پيوند كليه

THE STUDY OF FREQUENCEY OF MALIGNANCY AFTER KIDNEY TRANSPLANTATION

Kidney transplant recipients are prone to malignancies more than general population . These malignancies are one of the major causes of morbidity in these patients. The aim of this study was to determine the incidence of post transplant malignancies in Gol estal Hospital, Ahwas, and comparing it to other centers.in this prospective study , 210 transplanted patiens , consisting of 181 cases in Ahwaz and 29 cases in other centers ( Shiraz and Tehran ), were followed for one to eight years. ( Average period of follow up is 32 months). Of these 210 patients , 7 cases of malignancy were found (3.3%) , contributes to 6.5% of mobidity and mortality causes. The most common malignancy was kaposiʹs sarcoma (57%) lymphoma (29%) and skin malignancies (14%) . Significant difference existed in general incidence comparing to oversease studies as kaposiʹs sarcoma has high and skin malignancies has lower incidence than other studies performed in other centers . The short period of follow up and high percentage of live related donation( 30% ) can be the cause . Also the difference in the type of malignancies may be due to numerous hereditary familial , environmental & other unknowns agents .