بررسي حساسيت آنتي بيوتيكي سويه هاي باكتريال جدا شده از عفونتهاي دستگاه ادراري

Antibiotic susceptibility of bacteria isolated from urinary tract infection

Background: Worldwide researches show that there is increasing resistance among urinary tract pathogens to conventional drugs. The aim of this study is to obtain data on susceptibility patterns of pathogens responsible for urinary tract infections (UTJs) in Flavarjan to antimicrobial agents that are currently used for the treatment of UTIs. Materials and methods: In this cross sectional study, 209 uropathogenic organisms were collected during 8 months. Then, appropriate staining and biochemical techniques were applied for organism detection. Iodometric technique was used for betalactamase identification. Results: Escherichia coli (54.1%) was the most common etiological agent causing UTIs, followed by Klebsiella spp.(\5.$%), and Staphylococcus aureus{\0.5%). In contrast, coagulase-negative Staphylococci, Pseudomonas aeroginosa, Enterobacter spp., Proteus spp. and Enterococcuc were isolated from less than 6.0%of isolates. Most of uropathogenic isolates were resistant to antimicrobial agents such as Co-trimoxazole, Ampicillin and Nalidixic acid but Aminoglycoside and Quinolones were effective on these isolates. Iodometric analysis showed that ^-lactamases were present in 70.8% of isolates. Conclusion: With respect to the frequency of urinary tract infection and use of antibiotics, and also the pattern of drug use in different regions, the presence of resistant isolates could be predictable. However, appropriate antibiotic use could postpone their presence.