بررسي اثرات نيروزايي عصاره هيدرو الكلي ريشه گياه آدمك (Biebersteinia multifida DC) در موش آزمايشگاهي نژاد BALB/c

Effect of Bibersteinia multifida DC. root extract on physical stamina in male mice

Fatigue is the inability of body to retain energy during exercise. So far, anti- fatigue effects of many plants have been evaluated, and some of them are accepted in clinical studies. In the present research, the anti-fatigue effect of Bibersteinia multifida DC. root extract was studied on the performance of Forced Swimming Test (FST) and on blood biochemical parameters related to fatigue in mice including: Glucose (Glc) , blood urea nitrogen (BUN), creatine kinase (ck), lactic dehydrogenase (LDH), and total protein (TP). The root extract (4, 7, 10 mg/kg) was orally (Gavage) administrated to male mice for one week. A significant reduction in immobility time in FST was observed by 4 and 7 mg/kg of the root extract, compared with the control group. In addition, the hydroalcoholic plant extract increased serum of Glc and TP levels, while decreased serum CK and LDH levels significantly. Also the level of BUN did not change. The results predict a potential benefit of Bibersteinia multifida DC. root extract as an anti-fatigue treatment and for improving physical stamina