مقايسه اثرات دگزامتازون موضعي و داخل وريدي بر ادم و تريسموس به دنبال جراحي مولرهاي سوم نهفته فك پايين

The Comparison of Effects of Local and Intravenous Dexamethasone on Edema and Trismus Following Impacted Mandibular Third Molars Surgery

Background and Objectives: Post-operative edema and trismus are common following removal of impacted teeth. The aim of the present study was to compare the effects oflocal and intravenous (IV) dexamethasone on the edema and trismus following hard tissue impacted mandibular third molar teeth surgery. Materials and Methods: In this clinical trial, 20 patients were randomly selected and allocated into two treatment groups. Surgical removal of bilateral impacted mandibular third molars under local anesthesia were performed. Group A received 8rog IV dexamethasone and group B received 4mg local infilterated dexamethasone for each side. Edema was measured using both tape measure and srmography methods. In regards to trismus. interincisal mouth-opening was measured using a calibrated caliper pre-operatively and post-operatively. Data were statistically analyzed using MannWittney and Wilcoxon tests. Results: Both sonography and tape measure (method A) methods showed that the local dexamethasone was significantly more effective than IV dexamethasone in reduction of post-operative edema (p=O.OI2). Meanwhile. the difference of effectiveness between local and IV dexamethasone on the trismus was not statistically significant. Conclusion: The results indicated that the use of local dexamethasone is an effective therapeutical strategy in reduction of post-operative edema of mandibular third molar teeth surgery.