بررسي ميزان نتايج مثبت و منفي كاذب تست توبركولين در تشخيص پريكارديت سلي در بيماران مراجعه كننده به بيمارستان هاي امام خميني (ره) و مدرس تهران در سال هاي 1380 - 1383

Positive and negative false results of tuberculin test in diagnosing pericardiaI tuberculosis in Emam Khomeini and Modaress hospitals of Tehran (2004-4)

Introduction: Mycobacterium tuberculosis. Is one of the most common factors which causes pericarditis following suffering from lung tuberculosis. To diagnose pericarditi s caused by mycobacterium tuberculosis, methods like PPD test, culture and staining of pericardial fluid , biopsy of pericardial tissue and peR of pericardial fluid are used. In this study, level of specific sensitivity of PPD test for diagnosis of pericardial tuberculosis has been evaluated . MateriaJs&Methods: 100 patients admitted at the academic hospitals of Shahid Behshti and Irnan Kbomaini medieal universities underwent experimental observations for diagnosis of primary perieardial tuberculosis during 1981-4. First PPD test was done, then a sampling of pericardial fluid andʹ biopsy of pericardial tissue were accomplished. The pericard ial was used for fluid staining by Ziehl-Neelsen and culture on Leuin - Estein Jonson media. After fixation and H&E staining, the necessary studies continued to eonsider the cheesy granuloma and tuberculo sis bucilli. Findings: In this study, out of the 100 selected patients, 40 cases were diagnosed as suffering from perieardial tuberculosis by laboratory tests, all the cases were eomplaining of tuberculosis symptoms. Culture ofpericardial fluid in 18 patients (45%), and pericardial biopsy in 18 ones (45%), staining of pericardial fluid in 9 patients (22.5%) and tuberculin cutanous test in 30 patients (75%) proved positive, while false negative cutanous tuberculin test in] 0 patients (25%) and false positive results in (45%) ofpatients were significantly were achieved .