بررسي تاثير روغن حيواني بر پروفايل چربي خون و يادگيري اجتنابي غيرفعال در موشهاي صحرايي نر

Effect of Ghee Oil on Blood Fat Profile and Passive Avoidance Learning in Male Rats

Background and Objectives: Nutritional role of edible oils, which may induce diverse effects on nervous system. is one of the issues considerations in modem communities as well as our country. Tissue changes and thereby behavioral alteration are among these effects. In present study the effect of nutritional oils on serum lipid profile and memory was studied. Methods and Methods: Twenty Wistar rats in 2 equal nutritional groups were studied: I) Control group 2) Ghee oil group. After 5 weeks of taking their particular diets, rats tested by shuttle box system for passive avoidance learning. Then blood samples were obtained and lipid profile was determined using an autoanalaizer and Randox kits. Finally using SPSS software, TStudent and pearson method results were analyzed (p < 0.05 was considered as significant). Results: In ghee oil group based on HDL and LDL (which suggests propensity in arteriosclerosis) indicators as compared with control group was found to be useful for prevention of cardiovascular diseases. This oil induced positive effects on memory retrieval after 24 and 72 hours (P< 0.05). Conclusion: Based on the positive effects of ghce oil on memory and prevention of cardiovascular disease, we suggest to include ghee oil (even in small amounts) in the diet. The advisable amount added to family diet requires further investigations.