بررسي اثر چند فرآورده ضدعفوني كننده رايج بيمارستاني برضد سويه هاي سودوموناس ايروجينوزاي جدا شده از بيماران

Evaluation of Antibacterial Activity of Certain Disinfectants on Some Clinical Isolates of Pseudomonas aeruginosa

Background and Objectives: Nosocomial infections are one of the significant causes of mortality all over the world, but it can be easily managed by adequate application of disinfectants. The purpose of this study was to evaluate the bactericidal activity of some routine used disinfectants against clinical isolates of Pseudomonas aeruginosa. Materials and Methods: The susceptibility of 25 clinical isolates of P. aeruginosa to disinfectants namely germicide-P, cetrimide-C, povidone iodine and ethanol was determined by the standard suspension test as well as surfacc test. Also to evaluate the effect of organic load on the activity of the disinfectants, 5% bovine albumin was applied as dirty condition in standard suspension test. Results: According to the results of suspension test, the minimum bactericidal concentrations of all the tested compounds fell into use concentrations, i.e. 1/5, 1/120, 10% and 70° for germicide-P, cetrimide-C, povidone iodine and ethanol, respectively. Whereas the results of surface test that evaluated the ability of disinfectant to act against surface dried microbial load, were significantly different and showed various degrees of decline. Five percent organic load showed no significant difference in the results of AOAC test of any of the tested disinfectants against none of/5, aeruginosa isolates. Conclusion: All the tested isolates showed various degrees of susceptibility when treated with the use dilutions of germicide-P, povidone iodine and ethanol and only cetrimide-C in the dilution of 1:30, within its use dilution was able to eliminate all isolates.