عنوان مقاله :
اثر تعاملي تمرين هوازي و مصرف مكمل ويتامين E بر حذف MTDNA لكوسيتهاي خون انسان بعد از يك جلسه فعاليت وامانده ساز
عنوان به زبان ديگر :
The Interaction Effect of Aerobic Training and
Vitamin E Supplementation on mtDNA Deletion in
Human Leukocytes after Exhaustive Exercise
پديد آورندگان :
ميرزايي، بهمن نويسنده دانشگاه گيلان Mirzaei, B , سلامي ، فاطمه نويسنده Salami, F. , رحماني نيا، فرهاد 1343 نويسنده علوم انساني Rahmani Nia , F , جعفري، افشار نويسنده دانشگاه تبريز Jafari, A , هوشمند، مسعود نويسنده Houshmand, M. , شفا، مهدي نويسنده Shafa, M.
اطلاعات موجودي :
دوفصلنامه سال 1385 شماره 8
رتبه نشريه :
فاقد درجه علمي
كليدواژه :
تمرينات هوازي , فشار اكسايشي , فعاليت وامانده ساز , oxidative stress , ژنوم ميتوكندريايي , Exhaustive exercise , Common deletion (5kb) , Mitochondrial DNA (mIDNA) , حذف معمولي , Aerobic Training
چكيده لاتين :
The purpose of this study was to determine the interaction effect of 8 weeks aerobic
training and vitamin E supplementation on mtDNA deletion in human leucocytes after
exhaustive exercise .Forty untrained, healthy and non-smoker students (age of 21.3±1.3
yrs, weight of 74.2±14.4 kg & BF% of 17.9±6.1) voluntarily participated in this study
and randomly assigned to one of the 4 groups: (aerobic training+vitamin E), (aerobic
training+placebo), (vitamin E), and (placebo). Subjects completed an incremental cycle
ergometer test until exhaustion. The initial workload was 50W at 60 rpm for 5 min.
Then, workload was increased progressively by 25W every 5 min until exhaustion
while, the rpm was constant. Venous blood samples were collected I hour before and
immediately after exhaustive exercise. Subjects of the groups I and 2 were influenced
by independent variables during 8 weeks by 50-75% HRR (Carvonen method).Subjects
of the groups 3 and 4 didnʹt perform any regular exercise during the period of study. In
the groups of I and 3 subjects took a daily dose of 400 mg vitamin E. Subjects of the
groups 2 and 4 took placebo containing sucrose. Blood sampling and performing
exhaustive exercise were the same as prior to the study. The mtDNA deletion was
analyzed using Multiplex Polymerase Chain Reaction (PCR) method. The results of
Kruskal-Wallis and Sign test analysis demonstrated that there is a common deletion in
human leukocytes mtDNA after exhaustive exercise bout (p<0.05). However, no
significant differences were observed in mtDNA deletion after exhaustive exercise bout,
after 8 weeks study. Therefore, discussion about effect of training on mtDNA deletion
needs more studies.
عنوان نشريه :
نشريه علوم حركتي و ورزش
عنوان نشريه :
نشريه علوم حركتي و ورزش
اطلاعات موجودي :
دوفصلنامه با شماره پیاپی 8 سال 1385
كلمات كليدي :
#تست#آزمون###امتحان