برر سي ارتباط ضخامت آندومتر و تعداد فوليكول هاي غالب در ميزان حاملگي در 361 مورد IUI

Assessment of the relationship between endometrial thickness and number of dominant follicles in pregnancy rate among 361 intrauterine insemination cases

Introduction: The size of the follicles and endometrial thickness are two important factors in pregnancy rate of patients undergoing intrauterine insemination (lUI). The likelihood of ovulation increases with follicular diameter and the fecundity increases with endometrial thickness. The other important factor in lUI is the number of foIlicles. In this study, we investigated the role of the endometrial thickness and the number of dominant follicles on pregnancy rate in patients undergoing lUI. Materials and Methods: The study group was the patients who were undergoing lUI during 6 years period in Amir-al-Momenien Hospital of Semnan. Ovulation induction was launched for all patients and when there was appropriate endometrial thickness (2:6 mm) and at least one dominant follicle (~16 rnm) in trans-vaginal ultrasonography. Thirty six hours after injection of HCG, lUI was performed. After survey of patients file, the number of dominant follicles and endometrial thickness were recorded. Then the pregnancy rate between patients with equal or more than 3 dominant follicles or less than 3 dominant foIlicles and patients with equal or more than 7rnm endometrial thickness with less than 7 rnm. we used student t test for statistical analysis. Results: About 361 cases ofIUI were performed and pregnancy happened in 70 cases (19.4 %). In non-pregnant group (291 cases), 133 cases had equal or more than 3 dominant follicles and 158 cases had less than 3 dominant foIlicles. In pregnant group (70 case) 37 cases had equal or more than 3 dominant foIlicle and 33 cases had less than 3 dominant follicles in the time of HCG injection. Statistical analysis revealed no significant differences in pregnancy rate between two groups (p= 0.317). With regard to endometrial thickness, 222 cases had equal or more than 7 rnm endometrial thickness and 69 cases had less the 7 mm in non pregnant group (291 cases). In pregnant group (70 cases) 68 cases had equal or more than 7 mm endometrial thickness and 2 cases(2.8%) had less than 7 rnm. Statistical analysis showed a significant difference in pregnancy rate between two groups (P