تاثير كاربرد طولاني مدت زرشك سياه (Berberis vulgaris) بر برخي اجزاي سندرم متابوليك

Long-term Effects of Processed Berberis Vulgaris on Some Metabolic Syndrome Components

Introduction: Metabolic syndrome is complex of metabolic disorders that correlates with cardiovascular disease. This study aimed at investigating the effect of processed Berberis vulgaris (B.vulgaris) on some metabolic syndrome components. Materials and Methods: Participants, type2 diabetics, were recruited in a randomized controlled clinical trial (n = 57) and randomly assigned into three groups: 1) processed B.vulgaris (n =19), 2) apple vinegar group (n =19) and 3) control group (n ;;;;19). Height, weight, serum total cholesterol , HDL-, LDL-cholesterol, triglycerides, glucose and insulin concentrations were measured at baseline and at the end of the Bth week and BMI, total/HDL-cholesterol ratio and insulin resistance were estimated. Results: Processed B.vulgaris group showed no significant effects on BMI, total cholesterol, triglycerides and glucose concentrations, whereas LDL-cholesterol concentration (22.48±35.44mg/dl) and total/HDLcholesterol rat io (2.56±4.B7) s ignificantly decreased and HDL-cholesterol concentration (12.33±20.5Bmg/dl) increased (P