آنتي توكسوپلاسما آنتي بادي در زنان با سابقه سقط يا مرگ جنيني

Anti - toxoplasma antibodies in women with abortion or still birth

Introduction: Fetal loss and abortion are responsible for significant emotional distress for couples desiring children. Regarding the etiologic importance, this study has been carried out to determine the prevalence of anti-Toxoplasma gondii antibody in women with abortion. Material and Methods: This case control study was carried out in Shariatee hospital in Bandar Abbas university of medical sciences, during 2002-2003. 124 women with definite diagnosis of abortion or fetal loss as patients and 251 matched women with at least two successful deliveries and negative history of miscarriage as controls were studied. The sera of the patients and the controls were tested by ELISA method for determining anti-Toxoplasma gondii antibody IgG and IgM. Results: There was a significant difference between prevalence of anti-Toxoplasma gondii antibody IgG (P < 0.001) and IgM (P= 0.006) in the patients and the controls . Conclusion: The results of this study suggest that Toxoplasma gondii plays a significant role in abortion in this area of IRAN.