بررسي اثر برداشتن طحال بر علائم آزمايشگاهي بيماران مبتلا به پورپوراي ترومبوستيوپنيك ايديوپاتيكزاده پاشا

Effects of splenectomy on CBC changes in patients with ITP

Introduction: ITP is one of the most common cause of thrombocytopenia encountered in medical practice. The disorder has been estimated to affect approximately 1 in 10000 in the general population and to account for 0.18% of the hospital admissions. This study is performed to determine the response of the patients with ITP to splencetomy. Material & Methods: This is a descriptive analytical cross-sectional study. The hospital files of 20 patients with ITP who were splenctomized in two university educational hospital were studied during 4 years. The samples were collected by census and one file was excluded bacause of its deficiencey. The data were analyzed by using SPSS software. Results: The mean ITP value was 30928 ±14352 SD during the two days before operation versus 476809 + 83252 SD during the two days after it (P=0.000). The mean ITP value was 476809+83252 SD versus 381432+81265 SD during the two daysafter the operation and approximately one-year follow up, respectively (P=0.003). Conclusion: According to our results,splenectomy is a suitable treatment for the patients with ITP We suggest this procedure to all patients who are indicated in every age, because there is no correlation between its success and the patientʹs age, his response to previous medical treatments or diagnosis-splencetomy interval.