بررسي ميزان تاثير استفاده از استامينوفن ركتال در كاهش درد بعد از عمل كودكان

The effect of rectal acetaminophen on post operative pain control

Introduction: Like that seen in adults, under treatment of acute pain occurs in substantial percentage of children. Control of postoperative pain is important in the pediatric patients because poor pain control may result in increase morbidity or mortality. One of the most important and safe rote for postoperative pain control in pediatrics, is rectal administration of acetaminophen. The aim of this study was to compare the analgesic and side effects of rectal acetaminophen and intravenous pethidine. Materials and Methods: A randomized controlled trial was performed in 60 ASA I, pediatric patients (aged 1-10 years) candidate to minor abdominal surgery, under general anesthesia, given either acetaminophen 20mg/kg rectally after induction of general anesthesia, and intravenous pethidine 0.3 mg/kg at the end of operation. Analgesic efficacy was assessed using Faces Score. Extra pethidine was administered if Faces Score was > or = 3. Results: We analyzed data of all patients. There are no statistical differences regarding weight and age among two groups. Faces scores did not differ between acetaminophen and pethidine group at recovery room, 2 and 4 hour after operation (p>0.05). Mean pethidine requirement also did not differ among two groups (5.5±0.4 in acetaminophen group vs. 5.7±0.7 in pethidine group and p> 0.05). Conclusion: Administration of 20 mg/kg of rectal acetaminophen has a clear analgesic effect in minor surgery in children if administered at the induction of anesthesia. Moreover, children with adequate analgesia with acetaminophen have less postoperative pain scores, and nausea and vomiting.