فراواني فاكتورهاي خطر آترواسكلروز در فرزندان افراد مبتلا به سكته قلبي زودرس

Frequency of Risk Factors for Atherosclerosis in Children with Family History of Premature Myocardial Infarction

Background and objectives: Clinical manifestations of coronary artery disease such as myocardial infarction generally have onset from middle age onwards. However, studies indicate that the atherosclerotic process begins to develop during childhood. The purpose ofthis study was to evaluate the frequency of risk factors for atherosclerosis in children with family history of premature myocardial infarction in Arak city in 2007. Materials and Methods: This was a cross sectional study in which 209 children and adolescents aged 318 years with a family history of early onset myocardial infarction were selected base on convenience sampling. Total cholesterol, low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), triglycerides, blood pressure, weight and height and fasting blood sugar were investigated. Data were analyzed by SPSS. Results: The prevalence of hypercholesterolemia and hypertriglyceridemia were 28.2% and 20.1% respectively. 19.1% of these individuals had HDL-C values lower than 35mgldL. 19/1% of them had LDL-C levels higher than 129 mg/dl., 4/31% presented hypertension and 28/71% had excessive weight. There was no relationship between hyperlipidemia and fasting blood sugar. However, there was significant association between hyperlipidemia and level ofBMI and blood pressure (P