گزارش 31 مورد عوارض دارويي بستري شده در بيمارستان بوعلي سينا ساري

Report of thirty one admissions due to adverse drug reactions in Bo-Ali Sina hospital, Sari, Iran

Background and purpose: Adverse drug reactions (ADRs) are one of the leading causes of morbidity and mortality, worldwide. Mortality rate due to ADRs are ahead of pulmonary disease, AIDS, pneumonia and automobile accidents. This study evaluated the admission rates in a University teaching hospital related to ADRs. Materials and methods: During this retrospective study between 2001 and 2007, all patients admitted due to adverse drug reaction in Sari Bo-Ali Sina Hospital were evaluated. Results: In these years, 31 patients out of 71,680 were admitted, due to ADRs. Most common ADRs were skin reaction (74%) and fever (22%). Phenobarbital and penicillin were the most common drugs causing ADRs. Conclusion: Only 0.04% of hospital admissions were drug related, while reported admission due to ADRs in other countries were 2.4 to 6.2%. It appears that less drug-depended hospital admissions in Iran rational drug administration, but are due to lack of enough detection, records and reporting procedures.