مقايسه عود ناحيه اي، متاستاز و ميزان بقاء بين دو روش جراحي در درمان مرحله هاي I و II باليني سرطان پستان

Comparison of local recurrence, metastasis and survival rate between two surgical approaches in clinical stage I and II in breast cancer

Aims. In patients with stage I and II of breast cancer, two common approaches are used: breast conservative surgery (BCS) and modified radical mastectomy (MRM). This study compared some variables between these methods. Materials & Methods. In a cross-sectional descriptive analytic study, medical records of 242 females with stage I and II of breast cancer were analyzed, retrospectively. These patients were operated by two types of BCS and MRM surgery. Follow-up was performed via examination or telephone call. Frequency and mean of variables measured. Life table, caplan-mayer and cox regression test used to evaluate the survival rate. Results. 109 patients (45%) were undergone BCS and 133 patients (55%) MRM. The mean age of patients in BCS was 47.2+10.4 and in MRM was 49.4+11.8 (p=0.5). There was no significant difference in locoregional recurrence (BCS 2.5%, MRM 3.2%; p=0.8), 1-year survival rate (both 100%) and 3-year survival rate (BCS 93% and MRM 94%) between two groups. However, metastasis was significantly lower in BCS (7.3%) group than MRM (18%) group (p=0.01). Conclusion. BCS method is not increasing the risk of locoregional recurrence and metastasis and decreasing the survival rate, so considering cosmetic advantages, BCS can be performed safely.