مقايسه زمان نهفتگي و ميزان وقوع پتانسيل هاي عضلاني برانگيخته دهليزي در افراد هنجار و بيماران مبتلا به منير با علامت و بي علامت

Comparison of the prevalence and latency of vestibular evoked myogenic potentials in normal participants and symptomatic and asymptomatic Meniereʹs disease patients

Background and Aim: Vestibular evoked myogenic potentials (VEMP) originate from the saccule and the inferior vestibular nerve. In this study, the prevalence of VEMP and latency of the pi 3 and n23 were compared between three groups of individuals, including symptomatic and asymptomatic Meniereʹs disease cases and normal participants. Methods: This study was conducted on 42 cases with the mean age of 40.48 years; thirty were Meniereʹs disease patients, of which 19 were symptomatic and 11 were asymptomatic; twelve were normal participants. The VEMP were recorded with 500 Hz tone bursts at 120 dBpeSPL. Then the prevalence and latency of the waves were analyzed and compared in the three above mentioned groups. Results: The prevalence of VEMP in symptomatic Meniereʹs disease patients (52.6%) was significantly less than asymptomatic individuals (90.9%) and also normal subjects (100%)(p<0.05). There was no significant difference between latencies of the waves in these three groups (p>0.05). The latency of pi 3 for symptomatic, asymptomatic and normal participants was 16.41, 15.20 and 14.14 ms, respectively and the latency of n23 for these groups was 20.25, 18.77 and 18.50 ms, respectively. Conclusion: In Meniereʹs disease, after medical management, the succule probably regains normal function resulting in re-existence of VEMP. It seems that there is no change in the latency of the waves, most likely due to involvement of the inner ear and intactness of the nerve. VEMP may be a useful test for diagnosis of Meniereʹs disease and additionally for monitoring the trend of medical management.