مرکز منطقه ای اطلاع رساني علوم و فناوري - كاهش بروز عفونت ادراري در پسران ختنه شده

چكيده لاتين :

Background: Urinary tract infection (UTI) is common in childhood with serious sequelae. Among infants, boys are more likely to develop UTI. The aim of this study was to determine circumcision effects in decreasing UTI incidence and appropriate age of circumcision. # Methods: During a prospective study lasting 7 years, 166 boys with UTI, aged less than 6 years, were allocated into 2 groups. They had no urinary tract abnormalities. In the first group 79 boys ranging in age from 2 months to 5.5 years (mean 11.3 ± 3.1 mo) were circumcised after UTI treatment and then observed for 6 months with taking urinalysis (U/A) and urine culture (U/C) 1-2 times monthly. The second group consisted of 87 boys aged 40 days to 5.5 years (mean 12.1 ±3.4 mo). After treatment of UTI, the boys were observed 6 months with taking U/A and U/C, then circumcised and served for another 6 months. The incidence of UTI in the two groups was compared using Chi-square test. For comparing the incidence of UTI in 6 months before and 6 months after circumcision in the second group we used Mcnemar method. Findings: There was significant difference (P=0.009) in occurrence of UTI in first and second group. There was also significant difference (P<0.0001) in incidence of UTI in 6-month periods before and after the circumcision in second group patients. * Conclusions: The present study indicated that circumcision decreases the risk of UTI in boys, independent of age. Therefore circumcision should be considered in newborn period and any patient with UTI or urinary tract abnormalities. Routinely performing cystourethrography in boys with first attack of UTI without urinary tract abnormalities (proven by history, physical examination and sonography) is questionable and needs further studies