بررسي آلرژي زايي دانه هاي گرده ابريشم مصري (caesalpinia gilliesi) از تيره حبوبات (laguminosea)

Study of allergenicity of Caesalpinia gilliesii pollen grains of Leguminosae

Introduction: Caesalpinia gilliesii is an ornamental plant which is commonly used for urban landscaping because of its long blooming period (from May to October) and beautiful flowers. Aim: The main purpose of this research is to determine the allergenicity of the pollen grains of Caesalpinia gilliesii. Materials and Methods: Pollen extracts were prepared with 5%,7% and 9% concentration levels using Buffer Phosphate Saline (BPS) for the experiment. Each experiment was performed on four (4), male, 3-month-old, Hartley guinea pigs. The samples were exposed to the extracts via eyes, nose and also sub-intradermal injection. Three different concentration of extracts was injected intraperitoneal with a one-week interval in a three week period. Blood sample were taken by the end of the third week and serum levels of BS and eosinophil and IgE were measured. Results: The results indicated that the blood sugar concentration and eosinophil percentage were positively correlated with allergen extract concentration. There was no significant increase in serum IgE concentration. The insignificant changes in IgE serum levels indicate that the pollen extracts of this plant does not develop any allergic immune response . Conclusion: The present study suggests that Caesalpinia gilliesii does not develop significant allergenicity; so using this plant for landscaping urban areas would be harmless for allergen sensitive civilians.