كارايي بيوپسي مخروطي به روش منجمد در ارزيابي ضايعات اينترااپي تليال دهانه رحم

Efficacy of cone biopsy of uterine cervix during frozen section in evaluation of cervical intraepithelial neoplasia

Aims: The aim of this study was to determine the efficiency of conical biopsy of frozen cervix in patients with high-grade cervical intraepithelial neoplasia, in order to investigate the lesionʹs margin and to rule out invasive carcinoma.Materials & Methods: 20 patients of high grade intraepithelial neoplasia, who all underwent conical biopsy of frozen cervix, were studied cross-sectional from March 2008 until September 2009 and the results of frozen biopsy were compared with permanent biopsies in them. Results: 15 cases (75%) had completely the same results for frozen and permanent biopsies. In 2 cases, the degree of CIN was lower, in the other two cases it was higher and in one case it was the same. Only one case was found in which the FSE result was CIN III and the result of the permanent sections was reported invasive carcinoma that was significant regarding its clinical effect. The comparison of these two results with the Paired Sample T-test showed no significant difference between these two groups (p=0.716); the results of these two methods were quite related to each other (r=0.716). Conclusions: Frozen section is highly valuable in evaluation of high-grade cervical intraepithelial neoplasia in cervical biopsies and has considerable efficacy.