تاثير مكمل ال كارنيتين بر IL-6 و CRP طي يك دوره تمرينات شنا در شناگران مرد

The Effect of L-Carnitine Supplementation on IL-6 and CRP During Swimming Training Period in Male Swimmers

The purpose of this study was to investigate the effect of L-Carnitine supplementation on IL-6 and CRP during 6 weeks progressive swimming training in male collegiate swimmer. For this purpose, 19 volunteer college swimmers selected with physical characteristics mean (SD): weight 72.1±7.2 kg; age 22.2±1.2 years and V02max 50.2±3.1 and then divided L-carnitine (LC) group (n=10) and placebo (PL) group (n=9). Both group performed 6 weeks progressive swimming training, LC group (1000 mg/d by mouth over a period of 6 weeks) and PL group in same time use placebo. Blood sampling was performed on each subject 24 hours before the period began (Time 1) and end of 6th week (T2). Data analysis was conducted by independent and paired t-test. Results showed that free carnitine concentration significantly increased at the end of the 6th weeks in LC (27%), but significantly decreased in PL (34%). The changes of IL-6 and CRP concentration were non significant in LC in this training program, but significantly increased in PL in same time. The results of this study suggest that 6-weeks L carnitine loading decreased inflammatory proteins (IL-6 and CRP) during 6wk swimming training. Finally, it concluded L carnitine supplementation can improve immune system and antioxidant in athletic.