اثر 12 هفته فعاليت شديد هوازي و يك هفته بي تمريني بر غلظت آديپونكتين پلاسما،مقاومت به انسولين و حجم چربي مركزي و محيطي در مردان ميانسال چاق

Effect of 12 weeks High Intensity Aerobic Training and a week Detraining on Plasma Adiponectin, Insulin Resistance and Central and Peripheral Fat Volume in Obese Middle Aged Men

Studies have been shown that plasma adiponectin concentrations were reduced with obesity and exercise training may reduce adipose tissue and obesity. Although, it is not well known whether exercise-induced change in insulin resistance and adipose tissue increases adiponectin concentration. Thus the purpose of this study was to examine the effect of a 12-week high intensity aerobic training program and a week detraining on plasma adiponectin, insulin resistance and central and peripheral fat volume in obese men. Sixteen healthy obese middle aged men (aged 41.18±6.1 years; height 168.31 ±4.7 cm; BMI 31.5±3.9 kg/m2) participated as subjects in this study. Subjects were assigned to a training group (n=8) or control group (n=8) underwent a 12-week intervention, with a frequency of 4 d/wk and intensity corresponding to 75-80% individual maximum oxygen consumption for 45 min. After a 12-week intervention, subjects were prescribed to avoid any type of high intensity physical activ-ity for a week. The results showed that body weight, BMI, fat mass, body fat percent, central (visceral and subcutaneous) and peripheral subcutaneous fat volume, waist and hip circumstance, WHR fasting glucose and insulin and insulin resistance were decreased (P<0.01), and plasma adiponectin and maximum oxygen uptake were increased significantly (P<0.01) in the training group compared to control group after 12 weeks. After one week detraining, plasma adiponectin concentration and body composition in training group were maintained constant and was not changed significantly. On the other hand, inverse correlation were observed between plasma adiponectin and central (visceral and subcutaneous), peripheral subcutaneous fat volume and and fasting insulin (P<0.05). In conclusion, 12 weeks high intensity aerobic training increased plasma adiponectin and reduces the obesity (visceral subcutaneous fat volume) in obese middle aged men.