بررسي تهيه هيد روژل از جلبك سارگاسوم استان سيستان و بلوچستان ايران بوسيله پرتوهاي يونيزه كنند ه

Study of synthesis hydrogel from sargassum alga of Iranʹs Sistan and Balochestan by ionizing radiation

In this study, hydrogel as wound dressing was prepared with composite Poly(N-vinyl-2-pyrolidone)(PVP), Alginate and Polyethylenglycol (PEG) by ionizing radiation. Ionizing radiation was applied as a tool for initiation of crosslinking and sterilization of these materials. Alginate as sodium alginate was extracted from brown seaweed prepared from areas of Sistan and Balochestan. then identified by FT-IR and GPC method. The effects of irradiation dose at the range 10-40 KGy and prepared hydrogels was studied. Also the concentration of components were varied and these effects of components on the properties of hydrogels such as Gel Fraction, Degree of Swelling (DS), Hydration and Dehydration properties, and Microbial test were evaluated. Hydrogel membrane at the dose of 25 KGy exhibits the following properties. It is elastic, transparence, flexible, sterile and impermeable for bacteria. They absorb a high capacity of water, attachable to healthy skin and can easy to be removed. PVP and Alginate hydrogels alone donʹt have suitable properties the same as wound dressing when they are used together, better gel is obtained, because of the existence of alginate chains between PVP network.