ارزيابي ارتباط بين غلظت كورتيزول، گلوكز ، BHB و اوره خون د ر بزهاي آبستن و شيروار

Correlations among serum Cortisol, glucose, BHB and urea concentrations in pregnant and lactating goats

An investigation was designed to find out the concentrations and correlations among serum glucose, beta-hydroxybutyrate (BHB), urea and Cortisol concentrations in pregnant and lactating goats in 2006 in Urmia. Ninety five pregnant does and 54 lactating goats were selected. Jugular blood samples were collected from each goat. Blood glucose, BHB and urea concentrations were assessed by spectrophotometer methods using commercial kits (Runbut, UK and Pars Azmon, Iran), respectively. Cortisol was assessed by ELISA method using Cortisol kit (Human, Germany). Mean for serum Cortisol, glucose, BHB and urea concentrations for pregnant goats were 7.31ng/dl, 44.9mg/dl, 0.23mmol/l, 3.21mmol/l for lactating goats 6.94ng/dl, 48.9mg/dl, 0.27mmol/l and 4.09mmol/l, respectively. Mean comparison among pregnant and lactating goats showed significant differences (P<0.01) just for urea concentrations. There was a positive correlation between Cortisol and BHB (r=0.55, p<0.01), Cortisol and urea concentrations (r=0.51, p<0.01) in lactating goats. There were correlations between BHB and Cortisol in pregnant goats (r=0.76, p<0.01), BHB and Cortisol concentrations for overall goats (r=0.63, p<0.01). It is concluded that serum glucose, BHB, urea and Cortisol concentrations were at the level recommended in references and were not differ between pregnant and lactating goats except for urea concentration. The presence of correlations among serum parameters in lactating and pregnant goats could be useful in detection of the metabolic disorders. Subclinical pregnancy toxemia was not observed in goats.