بررسي ارتباط عفونت مجاري ادراري بدون علامت با برخي از متغيرهاي دموگرافيك در زنان باردار مراجعه كننده به مراكز بهداشتي شهرستان بهار در استان همدان

Association Between Asymptomatic Bacteriuria And Some emographic Variables in Pregnant Womenr Refered to Health Centers Affilited to Hamadan University of Medical Sciences

Introduction: Associatin between the frequency of asymptomatic urinary tract infection and pregnancy has always been a subject of interest to reserchers. The physiological changes assosiated with pregnancy under the effect of hormones result in changes of chemical composition of urine, which may facilitate bacterial growth. We conducted this study to determine the relationship between asymptomatic bacteriuria and some demographic variables in pregnant womens refered to health centers of hamadan university of medical sciences. Materials & Methods: In this study, midstream urine was collected from 377 pregnant women and streaked on blood agar and EMB medium agar and incubated at 37oC for 24 hours. Growth was considered significant if 105 CFU/ml (colony forming unit/ml) bacteria were present. Biochemical analysis of urine was carried out by urine strip method. For microscopic analysis, 10 ml of urine was centrifuged and the sediment was studied. Findings: The results showed that 10.1 percent of pregnant women had asymptomatic bacteriuria, and 73.7% have pyuria. Colonies were identified by biochemical tests, and the common uropathogens were E.coli 68.4%, S. epidermidis 10.5%, Klebsiella pnumonia 7.9%, S. fecalis 5.3%, Enterobacter cloacae, Morganella morgany and S. aureus each 2.5%. The organisms were further tested for antibiotic sensitivity using a disk diffusion method. Acording to the results, co~ trimoxazole was the best antibiotic, fowllowed by nitrofurantoin. Discussion &Conclusion: This syudy showe; al though, the pyuria is known as the best sign of inflammation in urinary tract, in case UTI is investigated on the base of pyuria, we will miss 26.3 % of UTI. Also, because of high frequency of asymptomatic bacteriuria (more than 6%), urine culture is suggested in all pregnant women at this region. Keywords: bacteruria, asymptomatic, pregnancy, uropathogen