بررسي ميزان شيوع و تعيين الگوي حساسيت آنتي بيوتيكي اسهال حاد باكتريايي دركودكان كمتر از 5 سال دربيمارستان هاي شهرستان لاهيجان

Survey of prevalence rate and antibiotic susceptibility patterns of acute infectious bacterial diarrhea in children of fewer than five years old in Lahijanʹs hospitals

Bacterial acute gastroenteritis is a common disease among children throughout the world, especially in developing countries. It usually is a self-limited disaese, but improper management of an acute infection can lead to a protracted courage. Aim of this research is study of microbial and non-microbial agents involved in gastroenteritis in children and rate of sensitivity amongst isolated bacteria against different antibiotics. In this study 405 samples of stools were collected from outpatient and inpatient children with gastroenteritis in Lahijanʹs hospitals. These samples were evaluated by macroscopic and microscopic conventional examinations, culturing and antibiogram. Amongst 405 conducted specimens, 134 samples were diagnosed as the microbial agents and the other 271 diagnosed as negative from the other of researchable agents. Amongst the microbial isolates, 120 cases (29.62 %) were related to the bacteria and the other 14 isolates (3.455%) were parasitic agents. Out of isolated bacteria , 91 isolates (75.83%) EPEC, 21isolates (17.5 %) Shigella spp. 6 isolates (5 % ) Salmonella spp. and 2 isolates (1.67 % ) Aeromonas spp. Were isolated . Among isolated protozoa , 12 isolates (85.72 % ) Giardia lamblia (64.29 % ) cysts and 21.43 % were trophozoites , 2 isolates (14.28 % ) Entamoeba histolytica trophozoites were confirmed. Based on Kirby bauer method for antimicrobial susceptibility testing, determined that the majority of isolated bacteria were sensitive to ciprofloxacin, gentamicin and sulfamethoxazole respectively, and the lowest rate of susceptibility for EPECs were against tetracycline and in the contrast Salmonellas and Shigellas had the most resistance rate to tetracycline, ampicillin, and furazolidone, whereas, Aeromonas species were completely resistant to Ampicillin, cephalotin and Amoxicillin. From statistically, and based on usage of X 2 test determined, there was no relation between disease and sex, whereas the most prevalence rate was occurred within the 33-43 age groups.