پديد آورندگان :
Shahba، Samira نويسنده Department of Microbiology, Faculty of Basic Sciences, Tehran Sciences and Research Branch, Islamic Azad University, Tehran, Iran Shahba, Samira , Bokaeian، Mohammad نويسنده , , Mozafari-Sabet، Nour Amir نويسنده Department of Microbiology, Iran University of Medical Sciences, Tehran, Iran Mozafari-Sabet, Nour Amir , Saeidpour-Parizi، Ali نويسنده Department of Internal Medicine, Zahedan University of Medical Sciences, Zahedan, Iran Saeidpour-Parizi, Ali , Bameri، Zakaria نويسنده Research Center for Infectious Diseases and Tropical Medicine, Zahedan University of Medical Sciences, Zahedan, Iran Bameri, Zakaria , Nikbin، Mohammad نويسنده Department of Phytochemistry, Faculty of Basic Sciences, University of Sistan, Zahedan, Iran Nikbin, Mohammad
كليدواژه :
Antimicrobial effect , Extract , Teucrium polium , urinary tract infection (UTI)
چكيده لاتين :
Background: The present investigation was conducted to study the antibacterial effect of aqueous, ethanolic and ethyl acetate extracts of Teucrium polium plant on the bacteria isolated from urine samples of those with UTI and to compare it with the effect of commonly used antibiotics in treating UTIs.
Materials and Methods: The antibiotic resistance of 147 strains of bacteria causing UTIs to the antibiotics selected through Kirby-Bauer disk diffusion method was determined. In the meantime, the aqueous, ethanolic and ethyl acetate extracts of T. polium plant were prepared. The antibacterial activity of these extracts was examined using Disk Diffusion Method. Finally, Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of antibacterial were determined using serial dilution method.
Results: T. polium extracts were merely effective in enterococcus and pseudomonas bacteria. In general, the MIC rate of aqueous extract in enterococcus was 1.25-5 mg/ml. The MIC rate of ethanolic extract for enterococcus was calculated as 10 mg/ml. The MIC of aqueous and ethyl acetate extracts for pseudomonas bacteria were achieved as 5 and 20 mg/ml, respectively. The MBC contents of aqueous and ethyl acetate extracts of teucrium for pseudomonas bacteria was 10 mg/ml in aqueous and 20 mg/ml in ethyl acetate extracts. The MBC content of extracts for enterococcus bacteria were 10 mg/ml in aqueous extract and 20 mg/ml in ethanolic extract.
Conclusion: T. polium extract can be effective in some bacteria causing urinary tract infection, especially enterococcus.
