الگوي حساسيت و مقاومت آنتي بيوتيكي در سويه هاي اشريشياكلي جدا شده از نمونه هاي باليني بيمارستان آراد تهران در سال 90-1387

Sensitivity Trend of E.coli

ABSTRACT Background and objective: The resistance to antibiotics among of pathogen bacteria is one of the main concerns of doctors all around the world, with consideration to different reports about E.coli bacteria’s sensitivity, this study was done to examine the pattern of sensitivity and antibiotic resistance of E.coli strains collected from clinical samples of patients hospitalized in Tehran’s Araad hospital. Materials and methods: In this descriptive examination, after extracting E.coli derivations from clinical samples (urine, catheter, phlegm, wound, abscess, vagina and blood), their sensitivity was measured using standard Kirby-Bauer test, in contract with following antibiotics Amikacin, Ciprofloxacin, Gentamicin, Imipenem, Sulfametoxazole Trimetoprime, Ceftriaxone and Cefotaxime. Results: Most of E. coli strains isolated were from urine samples every four years and the lowest of E. coli strains from vaginal samples. The most amount of sensibility to Imipenem and Amikacin and the most amount of resistant were seen to Sulfametoxazole-Trimetoprime and Ciprofloxacin. Conclusion: The results of this study are indicating that E.coli’s strains resistance has increased against Trimethoprim and Ciprofloxacin; presumably it is due to excessive consumption of these antibiotics. It is obvious that, with regard to increasing consumption of antibiotics, and consequently, augmentation of antibacterial resistance, control of this resistance factor is necessary and inevitable, so it is recommended to avoid unnecessary usage of antibiotics.