پديد آورندگان :
آزالي علمداري، كريم نويسنده استاديار دانشگاه شهيد مدني آذربايجان -, - , روحاني، هادي نويسنده - ,
چكيده لاتين :
Whether the metabolic reserve in generalized metabolic syndrome (MetS) induced by aerobic training modifies synergistically the circulatory corticosteroids, neurotrophins, and insulin resistance, still remains to be elucidated.Following to a graded exercise test (GXT) to exhaustion, middle-aged obese males with high number of metabolic risk factors (n=30, Age: 58.2±5.3 yrs, Weight: 95.0±8.3 kg, BMI: 31.5±1.5 kg/m2. Height: 173.0±7.0 cm and VO2peak: 20.0±4.2 ml/kg/min) were randomly divided into exercise and control groups and examined before and after 8 weeks of moderate intensity aerobic training (3 sessions per week; by 50-60% of V̇O2peak). Fasting blood samples were taken and the nutritional variables were also recorded at both occasions. The independent sample T test. Pearson Rheo, stepwise regression and ANOVA for repeated measurements were used to analyze the data. Exercise training not only increased insulin sensitivity, Vo2peak, serum nerve growth factor, brain derived neurotrophic factor, insulin like growth factor-1 and testosterone; but also decreased all the metabolic risk factors, body weight, Z MetS, and serum cortisol level (P<0.05). No significant differences were observed in daily amount of dietary protein, carbohydrate, lipid and the total consumed food through the study (P>0.05). Waist circumference, nerve growth factor and body weight were recognized as the most important predictors of testosterone/cortisol ratio (P<0.05). It can be concluded that aerobic training in generalized MetS, improves metabolic status and insulin resistance in addition to switching into an anabolic state.